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Creatine is in high demand among athletes as the food supplement that facilitates muscle growth. Original taste and low bioavailability of creatine has led to the development of such salts as creatine acesulfame and creatine saccharin.

Sweet Nutraceuticals LLC has developed a new approach to the taste modulation of creatine, in which creatine cation is coupled with anionic zero-calorie sweeteners such as acesulfame and saccharin. All synthesized salts are novel chemical entities, which deliver high solubility, stability and improved taste to creatine. Novel salts of creatine are a patent pending technology and Sweet Nutraceuticals owns an exclusive license to this patent, which covers a library of creatine and creatine ester ion conjugates with zero-calorie sweeteners.